The current medical bibliography equates the definition of Taybi-Linder syndrome with ODPD types I and III. Patients with ODPD present the same craniofacial characteristics but associated with skeletal abnormalities. Seckel syndrome was defined as severe IGR and postnatal dwarfism with severe microcephaly characterized by “bird-like face”, micrognathia, pointed nose, and receding forehead, associated with cognitive impairment and other abnormalities but with no skeletal malformations, except for occasional dislocation of the head of radius. 1,2 classified patients with microcephalic primordial dwarfism into two categories: Seckel syndrome and osteodysplastic primordial dwarfism (ODPD) that is further subdivided into three groups: I, II and III, primarily based on the skeletal characteristics. Notwithstanding the potential complications that the anesthesiologist may face, primarily related to airway abnormalities and the frequent association with neurological pathology, particularly epilepsy and neuroendocrine disorders, there are very few publications in the specialized bibliography.

It is characterized by intrauterine growth retardation (IGR), bone dysplasia (including the facial skeleton) and central nervous system malformations including brain malformations, refractory epilepsy, sensitive deficits, cognitive deficits and neuroendocrine disorders. The Taybi-Linder syndrome, also known as microcephalic osteodysplastic primordial dwarfism (MOPD) types I and III, is a rare, potentially inherited autosomal recessive condition.

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